WHAT HAPPENED IN 1516.
Look what happened the 1516.

The Bayerische Reinheitsgebot is signed in Ingolstadt. (23. April 1516)

Battle of Yaunis Khan: Turkish forces under the Grand Vizier Sinan Pasha defeat the Mameluks near Gaza. (28. October 1516)

The Ottoman Empire under Selim I defeats the Mamluk Sultanate and captures present-day Syria at the Battle of Marj Dabiq. (24. August 1516)

The Treaty of Noyon between France and Spain is signed. Francis I of France recognizes Charles's claim to Naples, and Charles V, Holy Roman Emperor, recognizes Francis's claim to Milan. (13. August 1516)

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